ACT for migraine: effect of acceptance and commitment therapy (ACT) for high-frequency episodic migraine without aura: preliminary data of a phase-II, multicentric, randomized, open-label study

DOI: https://doi.org/10.1007/s10072-019-03802-w

[Section 1] The result is a disabling condition, similar to that of patients suffering from chronic migraine, with the same clinical problems concerning treatment and manage- ment [616].

The treatment of this category of patients can be difficult and they need a multi- disciplinary treatment to learn techniques to manage their pain alternatively to med- ications and before than a chronic migraine condition with medication overuse has been induced.

It has been also reported that patients suffering from chronic migraine with med- ication overuse undergoing pharmacological prophylaxis and mindfulness practice showed similar changes in levels of biomarkers and underwent a significant improvement after treatment at long follow-up [617].

The aim of this study was to assess the feasibility of a novel ACT model for patients with high-frequency episodic migraine without aura (9/14 days per month) (with/without medication overuse) (according to the IHS beta 2013 criteria) and its effectiveness with respect to a standard treatment.

Acknowledgement A machine generated summary based on the work of Grazzi, Licia; Bernstein, C.; Raggi, A.; Sansone, E.; Grignani, E.; Searl, M.; Rizzoli, P. 2019 in Neurological Sciences.

Mindfulness and pharmacological prophylaxis after withdrawal from medication overuse in patients with Chronic Migraine: an effectiveness trial with a one-year follow-up